What We Do

The Centre of Excellence for Biomedical Tuberculosis (TB) Research (CBTBR) was established in July 2004 and signifies the governments commitment in finding solutions to one of the continents most threatening diseases.

SU Node

The research conducted within the SU node spans basic to translational and clinical research, largely focused on Tuberculosis and on the quality training of students.


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UCT Node

Research at the UCT Node is aimed at investigating aspects of the physiology and metabolism of M. tuberculosis of relevance to TB drug discovery, TB drug efficacy, mycobacterial persistence and TB transmission.

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Wits Node

Research at the Wits node covers identification and validation of novel drug targets for TB, with particular focus on peptidoglycan, DNA repair and mycobacterial oxidative phosphorylation as tractable areas for the discovery of new drugs

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Our Collaborators

The CBTBR is one of nine Centres of Excellence created through the National Research and Development Strategy of the South African government. The Department of Science and Technology (DST) are implementing the centres under the guidance of the National Research Foundation (NRF) of South Africa.


Breakdown of postgraduate students and postdoctoral fellows in the CBTBR in 2017

136 students
27% Postdoctoral fellows
32% PhD students
25% MSc students